早发型重度子痫前期合并胎儿生长受限产妇接受期待治疗对妊娠结局的影响

Effects of expectant treatment on pregnancy outcomes in maternal with early-onset severe preeclampsia and fetal growth restriction

目的探讨期待治疗对早发型重度子痫前期合并胎儿生长受限产妇妊娠结局的影响。方法选择我院2014年2月至2016年2月收治的早发型重度子痫前期合并胎儿生长受限产妇28例,根据产妇孕周将其分为甲组(孕周>32周,13例)和乙组(孕周≤32周,15例),给予两组产妇期待治疗,比较两组产妇并发症发生情况,胎儿及围产儿结局。结果两组产妇均发生胎盘早剥、肝肾功能受损、视网膜病变、低蛋白血症等并发症,但两组产妇并发症发生率比较,无显著差异(P>0.05);甲组发生胎死宫内、新生儿窒息、胎儿窘迫以及围生儿死亡发生率均显著高于乙组,差异均有统计学意义(P<0.05)。结论早发型重度子痫前期可严重影响产妇的妊娠结局,而给予产妇适当的期待治疗,可减少产妇并发症,改善围生儿结局,值得推广应用。

Objective To explore the effect of expectant treatment on pregnancy outcome in maternal with early-onset severe preeclampsia and fetal growth restriction. Methods Twenty-eight cases of women with early onset severe preeclampsia and fetal growth restriction in our hospital from February 2014 to February 2016 were selected. According to the gestational age, all the maternal were divided into group A （gestational age more than 32 weeks, 13 cases） and group B （gestational age less than 32 weeks, 15 cases）, and they were given expectant treatment. The complications and the fetal and perinatal outcomes of the two groups were compared. Results Placental abruption, liver and kidney dysfunction, retinopathy, hypoproteinemia and other complications occurred in the two groups, and there was no significant difference in the incidence of complications between the two groups （P〉0.05）. The intrauterine fetal death, neonatal asphyxia, fetal distress, perinatal mortality rates in the group A were significantly higher than those in the group B, and the differences were statistically significant （P〈0.05）. Conclusion Early onset severe preeclampsia has a serious impact on the outcome of pregnancy, but the expectant treatment in women with early-onset severe preeclampsia and fetal growth restriction can significantly improve the outcome of pregnancy, which is worthy of popularization and application.