3D-PDI联合血清AFP水平测定在孕晚期胎盘植入患者产前诊断中的价值

The value of 3D-PDI combined serum AFP level detection in the prenatal diagnosis of placenta accreta women in late-stage of pregnantThe value of 3D-PDI combined serum AFP level detection in the prenatal diagnosis of placenta accreta women in late-stage of pregnant

目的 分析三维能量多普勒超声（3D-PDI）联合血清甲胎蛋白（AFP）水平测定在孕晚期胎盘植入患者产前诊断中的价值.方法 选取2014年12月至2017年1月我院82例伴胎盘植入高危因素孕晚期孕妇的临床资料,按照分娩后的病理结果分为植入组（n=30）与未植入组（n=52）,统计两组患者血清AFP水平和3D-PDI诊断结果,并对比两者联合诊断结果与病理结果,单项诊断及两者联合诊断灵敏度、特异度、准确度.结果 植入组血清AFP水平明显高于未植入组（P＜0.05）;三维能量多普勒超声及血清AFP两者联合诊断灵敏度、准确度均高于单一诊断,且差异有统计学意义（P＜0.05）.结论 三维能量多普勒超声联合血清AFP水平测定可用作孕晚期胎盘植入孕妇产前诊断,其具有较高的灵敏度及准确度.

Objective To evaluate the value of three-dimensional power Doppler ultrasound （3D-PDI） combined serum al- pha-fetal protein （AFP） level detection in the prenatal diagnosis of placenta accreta women in late-stage of pregnant. Meth- ods From December 2014 to January 2017, 82 late-stage pregnant women with placental implantation risk factors in our hospital were divided into implant group （n=30） and non-implanted group （n=52） according to the pathological results after delivery, serum AFP levels, 3D-PDI diagnostic results were statistically analyzed between the two groups, and the sensitivity, specificity and accuracy of single diagnosis and combined diagnosis were compared. Results The serum AFP level in the im- planted group was higher than that in the non-implanted group （P〈0.05）; sensitivity and accuracy of the combined diagnostic were significantly higher than those of the 3D-PDI single or serum AFP single diagnosis, the prenatal differences were statis- tically significant （P〈0.05）. Conclusion 3D-PDI combined with serum AFP level detection could be used to diagnosis of pla- centa accreta women in late-stage of pregnant, with a quite higher sensitivity and accuracy.