抗凝联合降血脂治疗糖尿病动脉粥样硬化的疗效分析

Efficacy of Anticoagulation Combined With Hypolipidemic in the Treatment of Atherosclerosis

目的分析抗凝联合降血脂治疗糖尿病动脉粥样硬化的临床效果。方法选取2013年2月22日—2016年2月22日来我院就医的糖尿病动脉粥样硬化患者88例作为研究对象。通过动态化随机单双号分组的方法,将其分为两组。两组患者分别给予丹红注射液、奥扎格雷联合氟伐他汀治疗,分析两组患者空腹血糖、空腹胰岛素水平、血脂相关指标水平、颈动脉内膜中层厚度、斑块厚度的结果差异性。结果与对照组患者结果相比较,观察组患者的空腹血糖、空腹胰岛素水平、血脂相关指标水平、颈动脉内膜中层厚度、斑块厚度结果较优,组间对比,差异具有统计学意义(P<0.05)。结论奥扎格雷联合氟伐他汀治疗糖尿病动脉粥样硬化具有一定的应用价值。

Objective To analyze the clinical effect of anticoagulation combined with hypolipidemic therapy for atherosclerosis in diabetic patients. Methods 88 cases of patients with atherosclerosis and diabetes from 22 February 2013 to 22 February 2016 in our hospital were selected as the research object. And the patients were divided into two groups by dynamic randomized single-double grouping. The patients in two groups were treated with fluvastatin, ozagrel and danhong injection respectively. The levels of fasting blood glucose, fasting insulin, blood lipid-related indicators, carotid intima-media thickness and plaque thickness were analyzed in two groups. Results Compared with the control group, the fasting blood glucose, fasting insulin level, blood lipid-related index level, carotid intima-media thickness and plaque thickness were better in the observation group, the difference was statistically significant （P〈0.05）. Conclusion Ozagrel combined with fluvastatin have a certain value in the treatment of atherosclerosis in diabetes mellitus.