临产孕妇凝血指标检测及临床意义

Clinical significance of detecting the function of blood coagulation for parturient women

目的:探讨临产孕妇凝血指标检测的临床意义。方法:采用ACL9000全自动血凝仪检测临产孕妇和健康非孕妇凝血酶原时间(PT)、INR、活化部分凝血活酶时间(APPT)、凝血酶时间(TT)及纤维蛋白原(FIB)并进行分析。结果:与健康非孕妇比较,临产孕妇的PT、INR值明显降低;FIB值明显升高,差异有统计学意义(P<0.01)。APPT、TT检测结果无统计学意义(P>0.05)。结论:对临产孕妇凝血四项指标的检测,可早期发现凝血功能的改变,对预防DIC的发生和及时治疗,降低临产孕妇DIC的发病率和死亡率有重要意义。

Objective To explore the clinical significance to detecting the function of blood coagulation for parturient women.Methods Used ACL9000 automatic coagulometer to detect 202 parturient women and 81 healthy women who are not pregnant about their prothrombin time,INR,activated partial thromboplastin time,thrombin time and fibrinogen,and analyze and study them.Results Compared with the healthy women who are not pregnant,parturient women are obviously lower in PT and INR.But their FIB is much higher and the difference is statistically significant(P<0.01).However,the detecting results of APTT and TT are not statistically significant(P>0.05).Conclusion By detecting the function of blood coagulation for parturient women,we can find the changes of the function of blood coagulation before it is too late,which is important for us to prevent the occurrence of DIC and treat it in time.Thus,we can reduce the morbidity and mortality among parturient women.