无痛人流术中伍用咪达唑仑、芬太尼与乳化依托咪酯联合使用的麻醉效果观察

Effect of combined application of Etomidate,Midazolam Ng and Fentanyl on painless induced abortion

目的:观察乳化依托咪酯与伍用咪达唑仑、芬太尼联合使用对无痛人流手术的麻醉效果。方法:研究分为三组,咪达唑仑+芬太尼+乳化依托咪酯组(Ⅰ组),芬太尼+乳化依托咪酯组(Ⅱ组),单纯乳化依托咪酯组(Ⅲ组),分别观察患者SBP、DBP、HR及SpO2的变化、肌阵挛和恶心呕吐发生情况。结果:肌阵挛发生率分别为4%(Ⅰ组)、12%(Ⅱ组)、22%(Ⅲ组);中重度肌阵挛发生率Ⅲ组>Ⅱ组>Ⅰ组(P<0.01);恶心呕吐的发生率Ⅲ组>Ⅱ组>Ⅰ组(P<0.05)。结论:乳化依托咪酯配伍咪达唑仑和芬太尼能明显减少依托咪酯肌阵挛和恶心呕吐的发生率,可安全地应用于门诊短小手术的麻醉。

Objective To observe the effect of combined application of Etomidate,Midazolam Ng and Fentanyl on painless induced abortion.Methods The patients were divided into three groups,midazolam + fentanyl + emulsion etomidate group(Ⅰ group),fentanyl + emulsion etomidate group(Ⅱ group),emulsified etomidate group(Ⅲ group).Results Myoclonus rates were 4%(Ⅰ group),12%(Ⅱ group),22%(Ⅲ group);in the incidence of severe myoclonic group Ⅲ> Ⅱ group> Ⅰ group(P <0.01);nausea The incidence of vomiting in group Ⅲ> Ⅱ group> Ⅰ group(P <0.01).Conclusion Etomidate emulsion compatibility of midazolam and fentanyl can significantly reduce the Etomidate myoclonus and the incidence of nausea and vomiting,can be safely used in short outpatient surgical anesthesia.