药对白术-陈皮挥发油成分GC-MS分析

The GC-MS analysis of volatile oil from Atractylodes Macrocephala Koidz,Pericarpium Citri Reticulate and their mixed samples

目的:定性、定量分析药对白术-陈皮、单味药白术和陈皮的主要挥发油成分,探讨药对和单味药挥发油成分变化。方法:共水回流冷凝法分别提取单味白术、陈皮及药对挥发油、气相-质谱(GC-MS)检测,直观推导式演进特征投影(HEIP)法解析所得GC-MS数据,比较图谱差异,鉴别主要化学成分。结果:药对白术-陈皮主要组分中未发现新的结构类型化合物,挥发油化合物来源于单味药材,且主要为白术挥发油。结论:药对白术-陈皮挥发油化学成分变化属于物理配伍变化。

Objective To analysis the volatile components in herbal pair Atractylodes MacrocephalaPericarpium Citri Reticulatae(HP AM-PCR),single herb Atractylodes Macrocephala(AM) and Pericarpium Citri Reticulatae(PCR) quantitatively.Methods Volatile oil from above materials were obtained with water reflux condensation method;oil composition was detected by gas-mass spectrometry(GC-MS) and the data was analyzed with heuristic evolving latent projection(HELP);Comparing the difference between chromatographys to identify the main chemical constituents.Results There was no new compound found in herbal pair.The compounds were from single herbs.Conclusion Chemical changes in herbal pair AM-PCR were physical compatibility.