病理生理学的进步改变急性呼吸窘迫综合征的治疗策略

Optimization of acute respiratory distress syndrome therapy strategies with advances of pathophysiology

急性呼吸窘迫综合征(ARDS)是临床常见的呼吸衰竭,其病理生理学特征为肺容积明显减少,肺顺应性降低和肺通气血流比例失调。随着对ARDS病理生理认识不断进步,临床医师能采取更多的手段和措施对ARDS的肺不均一性进行监测,并对ARDS呼吸功能进行精准的评估和支持。因此,病理生理学的进步在逐渐改变目前人们对ARDS疾病发生发展的认识,并为ARDS的精准治疗提供了理论依据。

Acute respiratory distress syndrome （ARDS） is a common clinical respiratory failure with pathophysiologieal characteristics including reduced lung volume, decreased lung compliance and imbalanced pulmonary ventilation and perfusion. With the development of understanding in the pathophysiology of ARDS, clinicians have more and more methods to monitor lung heterogeneity and precisely assess and support the ARDS respiratory function. Therefore, the advances of pathophysiology are gradually changing the current understanding of ARDS, and provide the theoretical basis of ARDS precise treatment.