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中药灌肠联合血液透析治疗慢性肾衰竭疗效观察 被引量:8

Curative Effect Observation on Traditional Chinese Medicine Enema Therapy Combined with Hemodialysis in the Treatment of Chronic Renal Failure
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摘要 目的观察比较单纯血液透析与血液透析加载中药灌肠的不同方式治疗慢性肾衰竭的疗效。方法 112例患者按随机数字表法分为两组,每组56例。对照组采用单纯血液透析治疗,治疗组在血液透析间期加载中药灌肠治疗。按照对照组每周3次,治疗组每周2次的频率进行透析治疗,治疗周期均为2个月。治疗结束后比较两组血生化指标治疗前后变化情况及临床疗效。结果两组治疗后患者血肌酐、尿素氮均有明显降低;采用血液透析加中药灌肠治疗较单独使用血液透析组下降更明显,两组比较差异有统计学意义(P<0.05);两组血红蛋白(Hb)治疗后较治疗前升高,但差异无统计学意义(P>0.05),血红细胞(RBC)明显高于对照组,差异有统计学意义(P<0.05);主要并发症对照组包括低血压、高血压、低血糖和心律失常,治疗组主要包括低血压、高血压、心律失常,血液透析加中药灌肠治疗组略低,但两组比较差异无统计学意义(P>0.05)。结论在血液透析的间期加载合适的中药灌肠治疗能够发挥提升治疗效果的作用,同时能够降低血液透析的频率;因为样本有限,观察周期较短,血液透析加载中药灌肠治疗是否能够降低长期、频繁血透产生的并发症有待继续观察。 Objective To observe the curative effect of simple hemodialysis and hemodialysis combined with traditional Chinese medicine enema therapy in the treatment of chronic renal failure. Methods 112 patients were divided into two groups ac- cording to random number table, 56 cases in each group. The control group was treated with hemodialysis and the experimental group received traditional Chinese medicine enema in addition to hemodialysis. Patients in control group received three times hemo- dialysis every week and patients in experimental group received twice hemodialysis every week, the whole course lasting 2 months. The changes of indications in blood biochemical examination before and after treatment in two groups were compared after treat- ment. Results Serum creatinine and urea nitrogen of both groups decreased significantly after treatment. Compared with simple hemodialysis, hemodialysis combined with traditional Chinese medicine enema therapy reduced serum creatinine and urea nitrogen more significantly, there being statistically significant difference between two groups ( P 〈 0. 05 ). Hemoglobin ( Hb ) in both groups elevated after treatment, but the difference was not statistically significant ( P 〉 0. 05 ). Amount of red blood cell (RBC) in experi- mental group was significantly higher than that of control group, the difference being statistically significant( P 〈 0. 05 ). Main com- plications in control group included hypotension, hypertension, hypoglycemia and cardiac arrhythmia, but in treatment group main complications included hypertension, hypotension and cardiac arrhythmia. The incidence of complications in experimental group was slightly lower than that in control group, but there was no statistically significant difference between the two groups ( P 〉 0. 05 ). Conclusion Coordinating hemodialysis with appropriate traditional Chinese medicine enema can promote curative effect and in the meantime, reduce the frequency of hemodialysis. Owing to the limited sample and short observation period, whether traditional Chi- nese medicine enema combined with hemodialysis can reduce the complications contributed to long-term and frequent hemodialysis still need to be observed.
机构地区 朝阳市中心医院
出处 《四川医学》 CAS 2017年第6期671-674,共4页 Sichuan Medical Journal
关键词 慢性肾衰竭 血液透析治疗 中药灌肠治疗 chronic renal failure hemodialysis treatment traditional chinese medicine enema therapy
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