血清降钙素原超敏C反应蛋白和前清蛋白联合检测在呼吸道感染疾病中的诊断价值

The Combined Detection of Serum Procalcitonin Drop, High Sensitive C-Reactive Protein and Prealbumin in the Diagnosis of Respiratory Tract Infection

目的 探讨血清降钙素原、超敏C反应蛋白和前清蛋白联合检测在呼吸道感染性疾病中的诊断价值.方法 选取2016年1—12月在辽河油田总医院呼吸内科确诊为呼吸道细菌感染的208例患者为观察组,另选在体检中心进行体检的100例健康者为对照组,测定并比较两组血清降钙素原、超敏C反应蛋白和前清蛋白水平.结果 观察组血清降钙素原和超敏C反应蛋白水平高于对照组,前清蛋白水平低于对照组,差异均有统计学意义（P〈0.05）.观察组这三项指标的阳性率均高于对照组,差异均有统计学意义（P〈0.05）.结论 血清降钙素原、超敏C反应蛋白和前清蛋白联合测定,可作为呼吸道感染性疾病诊断和鉴别诊断的常规指标,对指导临床抗菌药物的合理使用具有重要意义.

Objective To investigate the diagnostic value of combined detection of serum procalcitonin （PCT）, high sensitive C-reactive protein （hs-CRP） and prealbumin （PA） for respiratory tract infection. Methods 208 confirmed cases of respiratory tract bacterial infection in Liaohe Oilfield General Hospital of 2016 were chosen as the study group, and another 100 healthy cases from the check-up center as the control group. Serum PCT, hs-CRP and PA level of the two groups were tested and compared. Results The level of PCT and hs-CRP in the study group were significantly higher than those in the control group, while the level of PA was lower than that of the control group. The positive rate of the three indexes in the study group was significantly higher than that in the control group. Conclusion The combined detection of serum PCT, hs-CRP and PA can be used routinely for the diagnosis and differential diagnosis of respiratory infectious diseases.