6Ward MM.Rheumatoid arthritis:Guidelines for the management of RA:breadth versus depth [ J ] .Nat Rev Rheumatol,2009,5 ( 6 ) :302-303.
7Katchamart W, Trudean J,Phumethum V, et al.Efficacy and toxicity of methotrexate ( MTX ) monotherapy versus MTX combination therapy with non-biological disease-modifying anti-rheumatic drugs in rheumatoid arthritis:a systematic review and meta-analysis Ann Rheum Dis,2009,68 ( 7 ) :1105-1112.
8Bongartz T, Sutton AJ,Sweeting MJ,et al.Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies:systematic review and meta-analysis of rare harmful effects in randomized controlled trial [ J ] .JAMA,2006,295 ( 19 ) :2275-2285.