急性心肌梗死患者脑尿钠肽及C反应蛋白变化与近期预后的相关性分析

目的 探讨脑尿钠肽（BNP）和C反应蛋白（CRP）的变化与急性心肌梗死（AMI）患者近期预后的关系.方法 96例AMI患者接受冠状动脉造影或冠状动脉CT检查,依据有无主要不良心血管事件（主要不良心血管事件包括心脏衰竭、严重心律失常、心肌梗死后心绞痛、再发性心肌梗死、心源性猝死）分为不良心脏事件组和无不良心脏事件组,检测并比较两组患者的CRP和BNP值.将各组测得的数据进行比较和统计学分析.结果 不良心脏事件组患者血清中BNP和CPR值均高于非不良心血管事件组,差异有统计学意义（P〈0.05）.结论 BNP和CPR水平可作为预测AMI患者短期预后的临床指标.

Objective To investigate the changes of BNP and CRP in acute paraquat poisoning patients and the correlation to the short-term prognosis. Methods 96 cases of AMI patients underwent coronary angiography or CT examination,on the basis of a no major adverse cardiovascular events（major adverse cardiovascular events including heart failure,arrhythmia,myocardial infarction angina,recurrent myocardial infarction, sudden cardiac death） were divided into benign cardiac event group and no adverse cardiac events group. The two groups were detected and compared with CRP and BNP. The measured data were compared and analyzed statistically. Results The levels of BNP and CRP in MACE group were significantly different from NMACE group（P〈0.05）. Conclusion BNP and CRP levels can be used as a clinical indicator to predict short-term prognosis in plateau AMI patients.