中老年高血压患者颈动脉斑块与hs-CRP的相关性分析

目的 通过检测中老年高血压患者血液中超敏C反应蛋白（hs-CRP）浓度,分析hs-CRP与颈动脉斑块的相关性.方法 选取2013年12月至2016年11月治疗的126例高血压病〉2级的中老年患者.行颈动脉超声检查有颈动脉斑块的65例为观察组,根据颈动脉斑块的严重程度将患者分成轻度狭窄、中度狭窄及重度狭窄三个亚组;行颈动脉超声检查无颈动脉斑块的61例为对照组.比较两组之间和各亚组之间血液中hs-CRP值.结果 颈动脉斑块组与对照组血液中hs-CRP相比较,有显著差异性（P〈0.05）;hs-CRP水平随颈动脉狭窄程度增加有升高的趋势.结论 中老年高血压病患者颈动脉斑块与hs-CRP有显著相关性.

Objective To analyze the correlation between hs-CRP and carotid artery plaque through detected the concentration of hs-CRP in the blood of the middle and aged hypertensive patients. Methods 126 middle and aged hypertensive patients（hypertension grade2 and above）were selected in our department from December 20l3 to November 2016. The neck vascular ultrasound found carotid plaque in 65 cases as carotid artery plaque group,according to the degree of impact on vascular patients were divided into three subgroups：mild stenosis,moderate stenosis,severe stenosis;61 cases were not found carotid plaque by cervical vascular ultrasound as control group. Hs-CRP value of the two groups and each subgroups were compared. Results Between the carotid artery plaque group and the control group,the levels of hs-CRP were significant1y different（P〈0.05）;hs-CRP was significantly increased with the increasing trend of the degree of carotid stenosis. Conclusion Among hypertensive patients,hs-CRP concentration and carotid plaque are positively correlative.