老年男性喝牛奶与其骨密度和骨转换标志物的关系

目的 调查老年男性喝牛奶与其骨密度、骨转换标志物的关系.方法 对505例老年男性喝牛奶的情况进行调查,并进行骨密度和骨转换标志物的检测,然后分析喝牛奶与骨密度、骨转换标志物的关系.结果 喝牛奶的老年男性骨质疏松率为10.86%,明显低于未喝牛奶的17.42%（P〈0.05）.与不喝牛奶的比较,喝牛奶老年男性的骨转换标志物（包括I型胶原羧基端肽β特殊序列、总I型胶原氨基端前肽、N端骨钙素和甲状旁腺素水平较低（P均〈0.01）.结论 老年男性坚持喝牛奶有助于降低其骨转换水平和骨质疏松发生率.

Objective To evaluate the relationship between drinking milk,bone mineral density and bone turnover markers in men aged 65 and over. Methods A cross-sectional survey was conducted in a cohort comprising 505 men. All participants underwent an questionnaire survey of drinking milk. Bone mineral density and bone turnover markers were conducted,and the relationship between drinking milk,bone mineral density and bone turnover markers were analyzed. Results Osteoporosis was found in men who had drunk milk,which was significantly lower than ones who had not （10.86%：17.42%,P〈0.05）. The the levels of serum C-telopeptide of type 1 collagen,N-terminal propeptide of type I procolagen,osteocalcin, and parathyroid hormone were significantly lower in old men who drunk milk（all P〈0.05）. Conclusion Drinking milk can decrease the level of bone turnover markers and decrease the incidence of osteoporosis in men aged 65 and over .