喉小涎腺导管癌1例

Minor salivary duct carcinoma of the larynx:a case report

1病例报告 患者,男,72岁,因声嘶1个月入院。患者1个月前无明显诱因出现持续性声嘶,伴有咽干,偶伴咽痒及咳嗽,无痰中带血。体检及电子喉镜示：右侧声带及前联合处黏膜表面不光滑,左侧声带表面光滑,双侧声带膜间部活动及闭合佳软骨间部活动及闭合可（图1）,电子喉镜下取病变处组织行病理检查示上皮中-重度非典型增生。

Salivary duct carcinoma（SDC）is a rare disease,especially in the larynx.From the pathology point of view,SDC histomorphology is very similar to breast ductal carcinoma.From the immunohistochemistry,epithelial antibodies are positive,but the SMA is negative.From the review of papers,total resection is the first choice for the treatment,but the local recurrence and distant metastasis are the main influence factors for survival rate.Now we still lack the clinical experience for such disease.