小剂量的地塞米松药物与甘露醇合用对口腔颌面部损伤早期肿胀的疗效

Effect of low dose of dexamethasone combined with mannitol on early swelling of oral and maxillofacial injuries

目的探究分析小剂量的地塞米松药物与甘露醇合用对口腔颌面部损伤早期肿胀的疗效。方法本次研究主体为2015年2月~2016年1月在湖北省黄冈市中心医院接受治疗的口腔颌面部损伤早期肿胀患者,共100例,采用信封式随机分组的方式将患者分为2组,每组50例,A组患者接受小剂量的地塞米松治疗,B组患者在此基础之上增加甘露醇进行治疗,比较2组患者的疗效与颌面部肿胀、疼痛改善情况。结果 B组患者的临床总好转概率与A组对比,明显较高;治疗后B组患者的水平方向距离与垂直方向距离、疼痛评分均明显较A组优异（P〈0.05）。结论小剂量的地塞米松药物与甘露醇合用对口腔颌面部损伤早期肿胀的治疗效果可观,值得在今后临床中进一步推广实施。

Objective To explore the effect of low dose of dexamethasone and mannitol on the early swelling of oral and maxillofacial injuries.Methods A total of 100 patients with oral and maxillofacial injuries who were treated in Huanggang City Center Hospital from February 2015 to January2016 were divided into two groups by means of an envelope randomized group. Group 50 patients,group A patients received low doses of dexamethasone treatment,B group of patients on the basis of increased mannitol for treatment,compared the efficacy of both groups of patients with maxillofacial swelling improved. Results The clinical general improvement probability of group B was significantly higher than that of group A,and the distance between the horizontal direction and the vertical direction of group B was significantly higher than that of group A（ P〈 0. 05）. Conclusion The combination of low dose dexamethasone and mannitol has a great effect on the early swelling of oral and maxillofacial injury,and it is worthy to be further implemented in the future clinical practice.