甘油果糖联合甘露醇治疗四肢骨折术后肿胀的疗效

Effect of glycerin fructose combined with mannitol in the treatment of postoperative swelling of extremities fractures

目的研究分析甘油果糖联合甘露醇治疗四肢骨折术后肿胀的临床治疗效果。方法选取浙江省义乌市中心医院于2015年2月~2017年2月收治的100例进行四肢骨折手术的患者作为本次研究过程中的研究对象,随机分为对照组和实验组2组,每组患者各为50例。对照组患者在骨折手术后进行甘露醇对患者进行消肿,实验组患者利用甘油果糖联合甘露醇对患者进行消肿。比较分析实验组与对照组患者患肢的肿胀程度。结果经过不同的治疗后,实验组患者发生不良反应的例数为0例,概率为0.0%,对照组患者发生不良反应的例数为5例,不良反应概率为10.0%。由此可得,实验组患者不良反应发生率显著低于对照组,差异具有统计学意义（P〈0.05）。实验组患者在手术后第6天、第7天、第8天以及第9天前臂患肢周径显著低于对照组患者,差异具有统计学意义（P〈0.05）。在手术后第8天以及8天后,实验组患者小腿患肢周径显著低于对照组,差异具有统计学意义（P〈0.05）。结论甘油果糖联合甘露醇治疗四肢骨折术后肿胀的临床效果较好,安全性较高,在很大程度上降低不良反应发生的概率。

Objective To study the effect of glycerin fructose combined with mannitol in the treatment of postoperative swelling of extremities fractures. Methods In Yiwu Central Hospital from February 2015 to February 2017 treated 100 cases of limb fracture surgery patients as the research object in the course of the study,were randomly divided into control group and experimental group two were 50 cases each. The patients in control group were treated with mannitol after fracture surgery,and the patients in the experimental group were treated with glycerol fructose and mannitol. Comparative analysis of the experimental group and control group of patients with limb swelling degree. Results After different treatment,the experimental group of patients with adverse reactions occurred in 0 cases,the probability was 0. 0%,the control group of patients with adverse reactions in the number of cases in the case of the number of patients with adverse reaction probability of 10. 0%,the number of patients with adverse reactions in the control group was5. As a result,the incidence of adverse reactions in the experimental group was significantly lower than that in the control group,with statistical difference（ P 〈0. 05）. In the experimental group,6 days after surgery,on the 7 day,the 8 day and the 9 day,the forearm circumference was significantly lower than that of the control group,with statistical difference（ P 〈0. 05）. On the 8 day after surgery and after 8 days,the leg circumference of the experimental group was significantly lower than that of the control group,with statistical difference（ P 〈0. 05）. Conclusion The clinical effect of glycerol and fructose combined with mannitol in treatment of limb swelling after surgery for fracture,high safety,reduce the probability of occurrence of adverse reactions to a great extent,is further applied in clinical significance.