膀胱冲洗对长期留置导尿患者尿路感染影响的Meta分析

Effects of bladder irrigation on urinary tract infection among patients with long-term indwelling catheter：a Meta analysis

目的 评价膀胱冲洗对长期留置导尿患者尿路感染的影响,为临床长期留置导尿患者是否进行膀胱冲洗以及冲洗的频率提供参考依据.方法 计算机检索中国期刊全文数据库（CNKI）、中国生物医学文献数据库（CBM）、Pubmed、Cochrane Library、EMBASE等数据库中1975年10月—2016年9月国内外膀胱冲洗对长期留置导尿患者尿路感染影响的随机对照试验（RCT）.采用RevMan 5.3软件对数据进行分析.结果 共纳入9个RCT研究,包含1722例患者.Meta分析显示,膀胱冲洗能够降低尿路感染的发生率,相比2次/d和1次/d,冲洗频率为2次/周降低尿路感染的效果最优.结论 膀胱冲洗可降低尿路感染的发生率,但需要选择合适的冲洗频率.

Objective To evaluate the effects of bladder irrigation on urinary tract infection （UTI） of patients with long-term indwelling catheter, and to provide a reference for identifying whether to provide long-term indwelling catheter and frequency of bladder irrigation.Methods Randomized controlled trail （RCT） data about the effects of bladder irrigation on UTI of patients with long-term indwelling catheter from October 1975 to September 2016 in CNKI, CBM, Pubmed, Cochrane Library and EMBASE were retrieved on the computer, and then analyzed with RevMan 5.3.Results Totally 9 RCTs were taken into consideration, involving 1722 patients. According to the meta-analysis, bladder irrigation could reduce UTI incidence, and twice a week of irrigation brought the best effect, compared with twice a day and once a day.Conclusions Bladder irrigation can reduce UTI incidence, but needs a proper frequency.