黄体酮对缓解输尿管结石疼痛的疗效观察

Efficacy of progesterone in the treatment of ureteral calculi

黄体酮是一种孕激素、助孕素,常用于月经失调、功血、闭经和黄体功能不全而引起的先兆性和习惯性流产等。近年来,在非妇产科疾患中,黄体酮又有许多新用途。本文主要探讨黄体酮在输尿管结石排石治疗中缓解疼痛的应用。选择200例输尿管结石非手术患者,随机分为2组,每组100人。对照组行输尿管结石非手术肾绞痛的常规治疗与护理,干预组在行输尿管结石非手术肾绞痛的常规治疗与护理外,肌肉注射黄体酮20mg,一天2次,共5d,2~5d后采用视觉模拟评分法(Visual analogue,VAS)来评估两组的疼痛水平。干预组患者疼痛水平明显低于对照组。结果表明黄体酮作为输尿管结石的辅助性治疗药物,在缓解输尿管结石患者的疼痛上疗效显著,提高了患者的生活质量。

The progesterone is progestogen,suppository,it commonly used for the threatened and habitual abortion caused by menstrual disorders,amenorrhea,dysfunctional uterine bleeding and luteal insufficiency.In recent years,in the gynecology and obstetrics disease,progesterone has many new uses.The application of progesterone in the treatment of ureteral calculi was investigated in this paper.200 Patients with ureteral calculi were selected then they were randomly divided into 2groups,each group of 100 patients.The control group received routine treatment and nursing of ureteral calculi of non operative renal colic,intervention group underwent not only routine treatment and nursing but also intramuscular injection of progesterone 20 mg,2times a day,a total of 5days,2-5days after the pain level of two group was assessed using visual analogue differentiate method（Visual analogue,VAS）.The pain level in the intervention group was significantly lower than that in the control group.The results showed that the effect of progesterone in the treatment of ureteral calculi was significant,and the quality of patients life was improved.