小剂量雌激素治疗绝经后泌尿系感染的效果分析

Study on the effect of small-dose estrogen on postmenopausal patients with urinary tract infection

目的:探讨小剂量雌激素治疗绝经后泌尿系感染的临床疗效。方法:选取在我院治疗的绝经后泌尿系感染反复发作的患者120例,随机分为观察组和对照组,每组60例。对照组给予常规抗感染治疗,观察组在常规治疗基础上给予小剂量雌激素(0.4 g·次-1,每日3次)治疗,比较两组的疗效、症状消失时间、尿白细胞计数等指标。结果:治疗后,观察组的总有效率为95.00%,高于对照组的75.00%(P<0.05);观察组症状消失时间为(3.10±0.52)d,明显短于对照组的(5.04±0.73)d,差异有统计学意义(P<0.05);治疗前两组尿白细胞比较,差异无统计学意义(P>0.05),治疗后两组尿白细胞均较治疗前有所降低(P<0.05)。结论:对绝经后泌尿系感染的患者给予小剂量雌激素能有效改善患者尿路症状,值得临床推广应用。

Objective： To investigate the effect of small-dose estrogen in the treatment of postmenopausal patients with urinary tract infection. Methods： One hundred and twenty cases recurrent urinary tract infection in our hospital were randomly divided into observation group and control group,60 cases in each group. The control group was given conventional anti-infection treatment,the observation group were added a small dose of estrogen treatment（ 0. 4 g estrogen per time,three times per day.） on the basis of the control group. The curative effect,symptoms disappeared time and white blood cell index in urine were detected and compared between the two groups. Results：After treatment,the total effective rate of the observation group was 95%,which was higher than that in the control group（ 75%）（ P〈0. 05）; the symptoms disappeared time of the observation group was（ 3. 10 ± 0. 52） d,which was significantly shorter than that of the control group（ 5. 04 ± 0. 73） d（ P〈0. 05）. The white blood cell in urine of two group before and after treatment had no statistically significant difference（ P〈0. 05）. After treatment the white blood cell in urine of the two groups had decreased than before treatment（ P〈0. 05）. Conclusion：Postmenopausal patients with urinary tract infection can be treated by small-dose estrogencan,which can effectively improve the clinical symptoms. It is worthy of clinical application.