新型一次性无肝素透析管路的设计及临床应用研究

The design and clinical application of a new type of disposable heparin free dialysis tube

目的 探讨新型一次性无肝素透析管路在尿毒症患者无肝素透析中的临床应用效果.方法 将110例无肝素透析患者,按照随机数字表法分为对照组和观察组各55例.在相同透析前肝素盐水预冲准备和透析中间断性0.9%氯化钠冲洗的基础上,对照组采用传统透析管路进行无肝素透析,观察组采用新型一次性无肝素透析管路进行无肝素透析.记录2组患者静脉壶堵塞、血液丢失和完成目标透析时间的例数.结果 对照组患者静脉壶堵塞6例,血液丢失6例,完成目标透析时间47例;观察组患者静脉壶堵塞0例,血液丢失0例,完成目标透析时间54例,差异有统计学意义（χ^2=4.407、4.407、4.356,P〈0.05）.结论 新型一次性无肝素透析管路在无肝素透析中,能减少患者血液丢失,延长治疗时间,而且操作简单,安全有效,具有很好的应用价值和应用前景.

Objective To investigate the clinical effect of a new type of disposable heparin freedialysis tube in uremic patients without heparin dialysis. Methods A total of 110 patients withoutheparin dialysis were divided into control group and observation group by random digits table method with55 cases each. Based on the same pre dialysis and dialysis for heparin saline flushing of discontinuoussaline on the control group using the traditional dialysis pipe for hemodialysis without heparin, theobservation group used disposable non heparin dialysis pipe for hemodialysis without heparin. The numberof patients with venous catheter blockage, blood loss and completion of dialysis time in two groups wasrecorded. Results The number of patients with venous catheter blockage, blood loss and completion ofdialysis time was 6, 6, 47 cases in control group and 0, 0, 54 cases in observation group. The differences were statistically significant （χ^2=4.407, 4.407, 4.356, P〈0.05）. Conclusions The new disposableheparin free dialysis tube can reduce the loss of blood and prolong the treatment time, and the operation issimple, safe and effective, and has good application value and application prospect.