基于数据挖掘技术分析腹泻型和便秘型肠易激惹综合征针灸使用规律

Analysis of Regularity of Acupuncture and Moxibustion in the Treatment of D-IBS and C-IBS by Data Mining

目的:通过文献分析临床针灸治疗腹泻型(D-IBS)和便秘型肠易激惹综合征(C-IBS)的经脉、腧穴选择特点和规律。方法:检索中国知网、万方、维普、Pubmed、Web of Science等数据库,收集2000—2016年针灸治疗D-IBS和C-IBS的临床研究报道,提取其所使用的针灸方式、经脉和腧穴。运用描述性分析、关联性分析和聚类分析研究其内在联系与规律规律,同时观察针灸治疗D-IBS和C-IBS的经脉、腧穴各自的规律和它们之间的差异。结果:共纳入针灸治疗D-IBS文献56篇、针灸治疗C-IBS文献6篇,D-IBS的治疗主要用针刺,临床以胃经和任脉的腧穴为主,如天枢、足三里、中脘,关联性分析发现胃经—任脉—脾经的为最常见的经脉组合,腧穴以足三里—天枢—太冲为主要关联群。聚类分析经脉主要分成2个核心聚类群,2个核心群组,腧穴则可以分成5个聚类群,5个核心群组。而C-IBS的研究则主要以悬灸为主,胃经、膀胱经的腧穴应用最多,如天枢、足三里、大肠俞、上巨虚,关联性分析发现经脉组合与D-IBS相同,也是胃经—任脉—脾经组合支持度和置信度最高,而腧穴则是以足三里—天枢的配伍最为常见。聚类分析则发现经脉、腧穴均可以分成2个核心聚类群,2个核心群组。结论:通过分析针灸治疗D-IBS和C-IBS的临床研究,认为虽然两者在针灸方法的使用上略微存在差异,D-IBS针灸并用,C-IBS以灸为主。但是在经脉和腧穴选择上却存在高度相似性。

Objective： To investigate the regularity of acupuncture and moxibustion treatment in diarrhea predominant irritable bow- el syndrome （D-IBS） and constipation predominant irritable bowel syndrome （C-IBS）. Methods：The research of acupuncture and moxibustion on D-IBS and C-IBS were collected from public databases including China National Knowledge Institute, Wanfang, VIP, Pubmed, Web of science etc. The approaches of acupuncture and moxibustion, the meridians and acupoints information was extracted. The differences in meridians and acupoints between D-IBS and C-IBS were studied by the descriptive analysis, correla- tion rule analysis clustering analysis. Results ： A total of 56 research of acupuncture and moxibustion on D-IBS, and 6 research of on C-IBS were involved in this study. In the studies of D-IBS, acupuncture was the most usual approach. The acupoints at the stomach meridian and conception vessel, such as ST 25, ST 36, CV 12 were used mostly often. By the correlation rule analysis, the combination of stomach meridian, spleen meridian, and conception vessel in the meridian analysis, but ST 36, ST 25 h, LR 3 in the acupoints analysis were mostly common. The cluster analysis found out that there were 2 effective clusters, 2 pairs of meridi- ans as well as 5 effective clusters and 5 pairs of acupoints. In the study of C-IBS, indirect moxibustion was the most usual ap- proach in clinic. The acupoints at the stomach and bladder meridians such as ST 36, BL 25, ST 37, and ST 25 were found most- ly. The correlation rule analysis and cluster analysis found similar results as D-IBS in the meridian acupoints, but ST 36 and ST 25 were mostly used. The cluster analysis found out that there were 2 effective clusters and 2 pairs of acupoints. Conclusion：Based on the analysis of acupuncture and moxibustion on D-IBS C-IBS, it was concluded that there is high similarity between the two dis-eases though there are different treating methods, D-IBS treatment often using combined acupuncture and moxibustion and C-IBS u- sing moxibustion.