46例脓毒症患者的中西医结合治疗效果观察

Observation on Integrated Western Medicine and Chinese Medicine in Forty-six Cases of Sepsis

目的:分析脓毒症患者应用中西医结合方案治疗的路径及效果。方法:选取我院2013年10月至2015年9月期间收治的92例脓毒症患者作为临床治疗对象,采用随机数字分组法将92例患者均分为治疗组与对照组2组。对照组46例患者均给予西医常规治疗方案,治疗组46例患者均于对照组患者治疗基础上给予中医辨证施治方案,观察2组患者临床治疗前后的体温、心率、呼吸、白细胞计数、胱抑素-C、氧合指数等指标改善情况,同时对比2组患者的痰、血培养结果,判断2组临床疗效差异。结果:经临床不同方案治疗后,2组患者的体温、心率、呼吸、白细胞计数、胱抑素-C、氧合指数等指标相比治疗前均告明显改善,但治疗组患者各项指标改善情况显著优于对照组患者(P<0.05)。治疗后2组患者痰、血培养总有效率对比,治疗组46例患者总有效率达86.95%,对照组46例患者总有效率为73.91%(P<0.05)。且中医疗效结果对比,治疗组患者治疗总有效率显著高于同期对照组患者,组间疗效差异显著,P<0.05,具有统计学意义。结论:脓毒症患者应用中西医结合治疗方案,具有着确切的临床疗效,可显著改善患者病症同时,助推患者预后康复,值得临床进一步应用推广。

Objective：To analyze the effect of integrated Chinese and western medicine in treating sepsis patients and its clinical pathway.Methods：A total of 92 patients with sepsis admitted into our hospital from October 2013 to September 2015 were collected, then randomly divided into observation group （n=46） and control group （n=46）.The control group was given conventional western medicine therapy, and on that basis, the observation group was given additional integrated Chinese and western medicine according to syndrome differentiation.Observe body temperature, heart rate, breathing, white blood cell count, the elf inhibition-C, oxygenation index, and so on before and after the treatment in both groups.Meanwhile, compare phlegm and blood culture results and clinical curative effects between the two groups.Results：After treatment, body temperature, heart rate, breathing, white blood cell count, the elf inhibition-C and oxygenation index of both groups were obviously improved, and the observation group was significantly better than the control group patients （P〈0.05）.After treatment, in the aspect of phlegm and blood culture, the total effective rate was 86.95% in the observation group, compared to 73.91% of the control group（P〈0.05）.Also, the results of total effective rate in observation group patients is significantly higher than that of the control group of the same period with statistical significance （P〈0.05）.Conclusion：Integrated western medicine and Chinese medicine has obvious curative effect on treating sepsis.It can relieve clinical symptoms and assist in prospective research, which is worthy of clinical population.