基于代谢组学方法的中医证候分类研究进展

Research Progress on the Metabolomics-based Study of the Classification of Traditional Chinese Medicine Syndromes

中医治疗疾病的优势主要体现在辨证分类基础上的个体化治疗上,但中医通过望、闻、问、切对患者进行证候分类主要以经验为主,缺乏客观依据和标准,使得中医证候进展一直缓慢,制约着其发展。作为现代一种全新的技术,代谢组学方法能够将证候与特异性的代谢产物结合在一起,从而为中医证候的客观化、标准化提供方法与手段,使中医证候的判识更加具有可信度。文章回顾了代谢组学方法在中医证候分类中的研究进展,以推进其在中医药领域中的深入应用与发展。

The advantages of traditional Chinese medicine（TCM）are mainly reflected in the individual treatment based on the dialectical classification,but herbalists through the hope,smell,question,cutting to the patient to carry on the syndrome classification are mainly based on experience,lacking of objective basis and standards,which make the progress of TCM syndrome slow,restricting its development.As a new technology,metabolomics can combine the syndrome with the specific metabolites that provides methods and means for the objective and standardization of TCM syndromes,making the recognition more credible.This article summaries the recent development of metabolomics in TCM syndrome classification research,in order to promote its application and development in the field of traditional Chinese medicine.