腹膜透析联合血液透析治疗慢性肾衰竭的临床疗效研究

Study on clinical curative effect of peritoneal dialysis combined with hemodialysis in the treatment of chronic renal failure

目的分析腹膜透析联合血液透析治疗慢性肾衰竭的临床疗效。方法 50例慢性肾衰竭患者,随机分成对照组及实验组,各25例。对照组患者给予腹膜透析治疗,实验组患者给予腹膜透析联合血液透析治疗,比较两组患者的临床疗效。结果治疗前,两组患者的肌酐、尿素氮、血红蛋白、白蛋白水平比较,差异均无统计学意义(P>0.05);治疗后,两组患者的肌酐、尿素氮、血红蛋白、白蛋白水平均较本组治疗前改善,且实验组改善程度优于对照组,差异均具有统计学意义(P<0.05)。实验组患者并发症发生率8.0%低于对照组32.0%,差异具有统计学意义(χ~2=4.50,P<0.05)。结论在对慢性肾衰竭患者进行治疗时,腹膜透析联合血液透析治疗能显著改善患者尿素氮、肌酐等指标,同时显著降低并发症发生率,具有临床推广和应用价值。

Objective To analyze the clinical curative effect of peritoneal dialysis combined with hemodialysis in the treatment of chronic renal failure. Methods A total of 50 chronic renal failure patients were randomly divided into control group and experimental group, with 25 cases in each group. The control group received peritoneal dialysis, and the experimental group received peritoneal dialysis combined with hemodialysis. Clinical curative effect was compared in two groups. Results Before treatment, both groups had no statistically significant difference in creatinine, urea nitrogen, hemoglobin and albumin level（P〈0.05）. After treatment, both groups had improved creatinine, urea nitrogen, hemoglobin and albumin level than before treatment, and the experimental group had better improvement degree than the control group. Their difference had statistical significance（P〈0.05）. The experimental group had lower incidence of complications as 8.0% than 32.0% in the control group, and the difference had statistical significance（χ^2=4.50, P〈0.05）. Conclusion For the treatment of chronic renal failure patients, combination of peritoneal dialysis and hemodialysis can significantly improve indicators of urea nitrogen and creatinine, and significantly reduce incidence of complications at the same time. So it has clinical promotion and application value.