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奥沙利铂联合卡培他滨二线治疗晚期胃癌的临床效果分析 被引量:1

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摘要 目的研究分析奥沙利铂联合卡培他滨二线治疗晚期胃癌的临床效果。方法 28例晚期胃癌患者,随机将患者分为观察组与对照组,每组14例。对照组在常规治疗的基础上应用卡培他滨进行治疗,观察组在常规治疗的基础上采用奥沙利铂联合卡培他滨进行治疗,对比分析两组患者的临床疗效。结果观察组患者治疗总有效率为64.29%,对照组为21.43%,比较差异具有统计学意义(χ~2=5.25,P<0.05)。观察组患者不良反应发生率为92.86%,对照组为85.71%,比较差异无统计学意义(χ~2=0.373,P>0.05)。结论奥沙利铂联合卡培他滨治疗晚期胃癌疗效较好,安全性高,可以在临床上推广应用。
作者 董海鹏
出处 《中国实用医药》 2017年第18期110-111,共2页 China Practical Medicine
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  • 1钱军,秦叔逵,梅静峰,陈映霞,邵志坚,何泽明.奥沙利铂联合卡培他滨二线治疗晚期胃癌的临床观察[J].中华肿瘤杂志,2004,26(12):746-748. 被引量:60
  • 2陈学明,宫海涛,俞淑花.奥沙利铂联合希罗达治疗晚期胃癌近期疗效观察[J].肿瘤防治杂志,2005,12(4):303-304. 被引量:16
  • 3Isikawa T, Sekiguchi F, Fukase Y, et al. Positive correlation between the efficacy of capecitabine and doxiflufidine and the ratio ofthymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts[J]. Cancer Res, 1998,58(4): 685-690.
  • 4Raymond E, Chaney S G, Taamma A, et al. Oxaliplantin: a reviewof preclinical and clinical studies [J]. Ann oncol, 1998, 9 (10):1053-1071.
  • 5Al-Batran S E, Atamaca A, Hegewisch-Beeker S, et al. Phase Ⅱtrial of biweekly infusional fluorouracil,folinic acid, and oxaliplatin in patients with advanced gastric cancer[J]. J Clin Oncol, 2004, 22(4): 658-663.
  • 6Kang H J, ChangH M, KimTW, et al, Phase Ⅱ study of capecitabine and cisplatin as first-line combination therapy in patients with gastric cancer recurret after fluoropyrimidine-based adjuvant chemotherapy[J]. Br J Cancer, 2005, 92(2): 246-251.
  • 7Raymond E;Chaney SG;Taamma A.Oxaliplatin:a review of preclinical and clinical studies[J],1998.
  • 8Roth AD;Ajani J.Docetaxel-based chemotherapy in the treatment of gastric cancer[J],2003(ZK).
  • 9Borner MM;Dietrich D;Stupp R.Phase Ⅱ study of capecitabine and oxaliplitin in first- and second-line treatment of advanced or metastatic colorectal cancer[J],2002.
  • 10Yeon Hee Park,Jae-Lyun Lee,Baek-Yeol Ryoo,Min-Hee Ryu,Sung Hyun Yang,Bong Seog Kim,Dong Bok Shin,Heung Moon Chang,Tae Won Kim,Young Jin Yuh,Yoon-Koo Kang. Capecitabine in combination with Oxaliplatin (XELOX) as a first-line therapy for advanced gastric cancer[J] 2008,Cancer Chemotherapy and Pharmacology(4):623~629

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