宫腔镜术联合药物三联疗法对不孕症合并子宫内膜息肉患者的助孕效果分析

Effect of hysteroscopy combined with drug therapy for the treatment of infertility with endometrial polyps

目的:探讨宫腔镜术联合黄体酮胶囊、裸花紫珠片三联疗法对不孕症合并子宫内膜息肉的助孕效果。方法:选择2013年6月至2015年6月于我院妇产科门诊就诊的子宫内膜息肉不孕症患者114例,采用随机数字表法分为观察组和对照组,对照组予宫腔镜术联合术后15d服用黄体酮胶囊,观察组在对照组基础上服用裸花紫珠片。比较两组患者妊娠率、疗效及子宫内膜息肉复发情况。结果:观察组57例患者中共有39例患者妊娠,未妊娠为18例,妊娠率为68.42%;对照组57例患者中共有20例患者妊娠,未妊娠为37例,妊娠率为35.08%,观察组妊娠率明显高于对照组;观察组总有效率为85.86%;对照组总有效率63.15%,观察组总有效率明显高于对照组;治疗后,观察组57例患者复发3例,复发率为5.26%,对照组57例患者复发16例,复发率为28.07%,观察组患者子宫内膜息肉复发率明显低于对照组。结论:宫腔镜术联合黄体酮胶囊、裸花紫珠片三联疗法可以降低子宫内膜息肉型不孕患者复发率,提高妊娠率。

Objectives： To investigate the pregnancy effect of hysteroscopy combined with progesterone capsules and callicarpa nudiflora for infertility associated with endometrial polyps. Methods： 114 infertile patients with endometrial polyps from June 2013 to June 2015 in our hospital were randomly divided into observation group and control group. The control group was treated with hysteroscopic surgery combined with 15 days＇ administration ofprogesterone capsules and the control group was given callicarpa nudiflora on such basis. The pregnancy rate,curative effect and recurrence of endometrial polyps were compared between the two groups. Results： The pregnancy rate in the observation group and control group was 68. 42%（ 39/57） and 35. 08%（ 20/57） respectively,with significant difference. The total effective rate was 85. 86% and 63. 15% in the observation group and control group respectively,with significant difference. The recurrence rate was 5. 26%（ 3/57） and 28. 07%（ 16/57） respectively in the observation group and control group respectively,with significant difference. Conclusion： Hysteroscopy combined with progesterone capsules and callicarpa nudiflora can reduce the recurrence of endometrial polyps and improve pregnancy rate.