健脾益气补血法对气血亏虚型帕金森病胃肠功能障碍的影响

Effect of Jianpi Yiqi Buxue Decoction on the Stomach Intestine Dysfunction of Syndrome of Qi and Blood Deficiency Type Parkinson's Disease

目的研究健脾益气补血法对气血亏虚型帕金森病胃肠功能障碍的疗效。方法方便选取2013年5月—2016年10月该院神经内科67例气血亏虚型帕金森病胃肠功能障碍患者随机分为两组,对照组35例予神经内科常规治疗,治疗组32例在神经内科常规治疗基础上予健脾益气补血汤煎服治疗。结果治疗后治疗组统一帕金森病评定量表第三部分(UPDRSⅢ)为(17.16±3.08)分、自主神经症状问卷量表为(13.37±8.16)分、胃肠道症状积分为(7.72±2.08)分,低于对照组的(19.46±4.60)分、(20.81±2.36)分、(10.60±3.53)分,组间差异有统计学意义(P<0.05),治疗后治疗组中医老年颤证诊断和疗效评定标准判定总有效率96.8%,对照组为77.1%,两组比较差异有统计学意义(P<0.05)。结论气血亏虚型帕金森病胃肠功能障碍予健脾益气补血法治疗效果明显。

Objective To research the curative effect of jianpi yiqi buxue decoction on the stomach intestine dysfunction of syndrome of qi and blood deficiency type Parkinson＇s disease. Methods Convenient selection 67 cases of patients with qi and blood deficiency type Parkinson＇s disease treated in our hospital from May 2013 to October 2016 were randomly divided into two groups, the control group with 35 cases adopted the routine treatment, while the treatment group with 32 cases adopted the jianpi yiqi buxue decoction. Results After treatment, the UPDRS Ⅲ, autonomic nerve symptom questionnaire and gastrointestinal symptom scores in the treatment group were low, er than those in the control group[（17.16±3.08）points,（13.37 ±8.16）points,（7.72 ±2.08）points vs（19.46 ±4.60）points,（20.81 ±2.36）points,（10.60 ±3.53）points], and the differences were statistically significant（P〈0.05）, after treatment, the total effective rate of senile tremor syndrome diagnosis and curative effect evaluation standards in the treatment group was 96.8% in the treatment group and 77.1% in the control group, and the difference was statistically significant（P〈0.05）. Conclusion The effect of jianpi yiqi buxue decoction on the stomach intestine dysfunction of syndrome of qi and blood deficiency type Parkinson＇s disease is obvious.