超声支气管镜引导下经支气管肺活检术在肺周围型病变诊断中的应用

Diagnostic value of endobronchial ultrasound-guided transbronchial lung biopsy in peripheral pulmonary lesion

目的探讨超声支气管镜引导下经支气管肺活检术(endobronchial ultrasound-guided transbronchial lung biopsy,EBUS-TBLB)在肺周围型病变诊断中的应用价值。方法 2011年9月至2015年9月于本院诊断为肺周围型病变的338例患者随机分为对照组和观察组,每组各169例。对照组行CT引导下经皮肺穿刺(computed tomography-guided percutaneous needle biopsy,CT-PNB),观察组行EBUS-TBLB。记录并比较两组的诊断阳性率及并发症发生率。结果观察组诊断阳性率为84.6%(143/169),高于对照组(69.2%,117/169),差异有统计学意义(P<0.05)。观察组并发症发生率为7.7%(13/169),低于对照组(14.8%,25/169),差异有统计学意义(P<0.05)。结论在肺周围型病变的诊断中应用EBUS-TBLB能提高诊断阳性率,减少并发症的发生,安全性较好,值得临床推广。

Objective To evaluate the diagnostic value of endobronchial ultrasound-guided transbronchial lung biopsy( EBUS-TBLB) in peripheral pulmonary lesion. Methods 338 patients with peripheral pulmonary lesion from September 2011 to September 2015 were randomly divided into two groups. The control group( n = 169) was treated with computed tomography-guided percutaneous needle biopsy( CT-PNB),and the observation group received EBUS-TBLB. The diagnostic yield and complications of the two groups were also investigated and compared. Results The diagnostic yield of the observation group( 84. 6%,143/169) was higher than that of the control group( 69. 2%,117/169)( P < 0. 05). The complication rate of the observation group( 7. 7%,13/169) was significantly lower than that of the control group( 14. 8%,25/169). Conclusion EBUS-TBLB is effective and safe for diagnosing peripheral pulmonary lesion,which is worthy of widely clinical promotion.