稳心颗粒联合美托洛尔治疗高血压心脏病合并室性早搏的临床研究

Curative effect of wenxin granule combined with metoprolol on patients with hypertensive heart disease complicating premature ventricular contraction

目的探讨稳心颗粒联合美托洛尔治疗高血压心脏病合并室性早搏的疗效。方法将近年来的72例高血压心脏病合并室性早搏患者分成两组,对照组采用常规治疗和美托洛尔口服治疗,观察组在此基础上给予稳心颗粒治疗。观察两组的治疗效果,总结临床经验。结果两组在总有效率、早搏控制时间、早搏控制率、治疗依从性和心血管事件发生率方面比较,差异有统计学意义(P<0.05);两组不良反应率比较,差异无统计学意义(P>0.05)。结论采用稳心颗粒联合美托洛尔治疗高血压心脏病合并室性早搏,能迅速且较好地控制早搏,提高治疗依从性,降低心血管不良事件的发生率,且不良反应较轻。

Objective To explore the curative effect of wenxin granule combined with metoprolol on patients with hypertensive heart disease complicating premature ventricular contraction（ PVC）.Methods Seventy-two patients diagnosed with hypertensive heart disease complicating PVC in recent years were divided into two groups. Conventional therapy and oral medication of metoprolol were adopted by the control group while the observation group was given additional treatment of wenxin granule besides therapies of the control group. The curative effect was observed in the two groups and clinical experience was summarized. Results There were statistically significant differences in the total effective rate,control time and control rate of PVC,treatment compliance and incidence of cardiovascular events between the two groups（ P〈0. 05）. The difference of the rate of adverse reactions was not statistically significant between the two groups（ P〉0. 05）. Conclusion For the patients with hypertensive heart disease complicating PVC,the combined therapy of wenxin granule and metoprolol can control PVC rapidly and effectively,improve therapy compliance,reduce the incidence of cardiovascular events,and decrease the rate of adverse reactions.