牙周牙髓联合病变激光与药物辅助治疗的对比研究

Comparison of dual-wavelength laser with Minocycline Hydrochloride for treatment of periodontal endodontic lesions

目的探讨双波长激光对比盐酸米诺环素治疗牙周牙髓联合病变的优越性。方法收集牙周源性牙周牙髓联合病变患者43例共48颗患牙,随机分为实验组和对照组。实验组掺铒钇铝石榴石(Er:YAG)消毒根管+掺钕钇铝石榴石固体激光(Nd:YAG)处理牙周袋;对照组碘伏消毒根管+盐酸米诺环素牙周袋上药。按视觉模拟评分法(VAS)观察两组治疗后1天疼痛差异,对比两组1周、2周、3周、3个月和6个月后牙周袋深度(PD)、牙周附着水平(CAL)、牙齿松动度,评价两组疗效。结果两组治疗后1天疼痛比较,差异有统计学意义;不同时间PD、CAL静息状态下VAS评分比较,差异有统计学意义(P<0.05);两组牙齿松动度比较,差异有统计学意义(P<0.05);实验组疗效优于对照组。结论双波长激光优于盐酸米诺环素治疗牙周牙髓联合病变素,临床应用前景良好。

Objective To observe the advantages of dual-wavelength laser over Minocycline Hydrochloride in the treatment of periodontal endodontic lesions. Methods In this study 48 teeth were collected from 43 patients with periodontal endodontic lesions and randomly divided into 2 groups. In the experiment group, Nd：YAG was used to disinfect the root canals, and Er：YAG laser irradiation was utilized to treat periodontal pockets. In the control group, iodophor was applied to root canal preparation, and Minocycline Hydrochloride was used to treat periodontal pockets. Using Visual Analog Scale （VAS） the difference in pain was observed between the two groups 1 day after treatment. Periodontal pocket depth （PD）, periodontal attachment level and tooth mobility were compared between the two groups after 1, 2 and 3 weeks, 3 and 6 months; then the efficacy was evaluated. Results The pain relief 1 day after treatment was significantly different between the two groups. There were significant differences in PD, periodontal attachment level and resting state VAS score between the two groups. The treatment of PD, periodontal attachment level and loosening of teeth was more efficient in the experimental group compared to the control group. Conclusions Combination of Er：YAG laser and Nd：YAG laser is better than Minocycline Hydrochloride for the treatment of periodontal endodontic lesions.