慢性萎缩性胃炎患者临床流行病学分析

Clinical characteristics of chronic atrophic gastritis patients in Heilongjiang province

目的了解慢性萎缩性胃炎(CAG)的临床特征。方法随机抽取2011年6月—2016年6月在黑龙江省大庆油田总医院行胃镜和胃粘膜检查的2 532例患者的临床资料,分析CAG的流行病学特点。结果 2 532例患者中,CAG患者523例,占20.66%,25例CAG患者因个人原因未能完成调查,最终纳入研究者498例。498例CAG患者中男性302例(60.64%),女性196例(39.35%),男女比例为1.54:1;CAG在30岁之前患者中的构成比为7.83%,在30岁以后呈直线上升,并在51~60岁达到发病高峰,60岁后逐渐下降。CAG患者中有幽门螺旋菌感染、吸烟、饮酒、饮食不规律以及水果摄入量低、腌制食品摄入量高和新鲜蔬菜摄入量低的患者所占比例明显高于无幽门螺旋菌感染、不吸烟饮酒、饮食规律以及水果摄入量高、腌制食品摄入量低和新鲜蔬菜摄入量高者(P<0.05)。结论黑龙江地区CAG的发病率较高,且多与该地区生活饮食习惯有关,应引起重视并采取相应预防对策减少CAG的发生。

Objective To explore the clinical characteristics of chronic atrophic gastritis（CAG）patients in Heilongjiang province.Methods Medical records of 2 532 patients who underwent endoscopy and gastric mucosal biopsy in a hospital from June 2011 to June 2016 were randomly selected and those diagnosed with CAG were surveyed with a questionnaire and epidemiological characteristics of the CAG patients were analyzed.Results Among the patients,523 （20.66%） were diagnosed with CAG and of the CAG patients,25 did not complete the survey because of personal reasons.For the 498 CAG patients included in the analysis,302 （60.64%）were male and 196 （39.36%） were female,with a male to female ratio of 1.54：1.The ratio of the CAG patients aged 51-60 years was the highest and the ratio of those aged 〉60 years decreased gradually;of the CAG patients,only 7.83% was less than 30 years old.Significantly higher prevalences of Helicobacter pylori infection,smoking,alcohol drinking,irregular diet behavior,high intake of pickled foods,and low intakes of fruit and fresh vegetables were reported by the CAG patients （P〈0.05 for all）.Conclusion The prevalence rate of CAG is high in Heilongjiang province and the prevalence is related to lifestyle and dietary behaviors.The results suggest that corresponding preventive measures should be taken to reduce the occurrence of CAG.