利用三维超声Oblique成像技术观察胎儿透明隔腔异常的价值

The value of the Oblique of three-dimensional ultrasonography in diagnosis of fetal cavum septum peilucidum

目的探讨超声任意剖面成像（Oblique）技术对胎儿透明隔腔异常的监测价值。方法采用三维经腹超声对产前二维超声显示透明隔腔异常的38例胎儿进行颅脑重点观察与Oblique成像，并与MRI检查、产后追踪随访结果进行对比总结分析。结果38例胎儿产前颅脑三维超声显示透明隔腔异常如下：①透明隔腔消失21例，其中单纯性透明隔消失10例，视隔发育不良1例，胼胝体缺失10例（包含完全性胼胝体缺失9例，部分性胼胝体缺失1例）。②透明隔腔减小12例，其中单纯性透明隔腔减小9例，伴有部分性胼胝体缺失3例。③透明隔腔增宽5例，均伴有韦尔加腔增大。35例与MRI检查结果一致，两种方法的诊断符合率差异无统计学意义（P〉0．05）。结论应用三维超声Oblique成像能清晰显示胎儿透明隔腔及胼胝体结构，为进一步诊断具体病变提供了确切的依据。

Objective To evalute the clinical significance of the Oblique view of three-dimensional ultrasonography（3DUS） in diagnosis of the fetal cavum septum pellueidum（CSP） malformation. Methods Thirty-eight cases of fetuses with the CSP malformation, found originally by trans-abdominal two dimensional ultrasonography（2DUS）, were scanned using Oblique of trans-abdominal 3DUS. The results were compared with MRI inspection and post-natal follow-up. Results Thirty-eight fetuses suspected with 3DUS Oblique were fully confirmed by autopsy and MRI, the distribution of CSP malformation included ： （1） Twenty-one cases with absence of septum pellucidum（ASP）, among them 10 cases with isolates of septum pellucidum, 1 case with septooptic dysplasia（SOD）, 10 cases with agenesis of corpus callosum（9 complete agenesis of corpus callosum and 1 partial agenesis of corpus callosum. （2）Twelve cases with shrinkage of them 9 simple shrinkage and 3 partial agenesis of corpus callosum respectively. （3） Five cases with enlargement, all of which also with increasing sizes of cavum vergae. Thirty-five cases are consistent with MRI observations. The diagnosis consistency differences between both methods were not significant. Conclusions 3DUS Oblique view can reveal the structure of fetal cavum septum pellucidum and corpus callosum clearly, which enable more accurate prenatal counseling and boild firm base for further diagnosis.