汤剂中天麻不同煎服法对临床药效的影响研究

Study of the Efficacy of Different Decocting and Dosing of Gastrodia Elata in Decoction on the Clinical Effect

目的:采用半夏白术天麻汤治疗高血压,观察其中天麻采用不同的煎服法对临床药效的影响。方法:将原发性高血压患者100例随机分为观察组和对照组。观察组50例采用改良后煎服法,对照组50例采用传统煎服法,观察两组的治疗有效率及治疗后NO、ET-1等指标。结果:观察组治疗有效率显著高于对照组治疗有效率,P<0.05,差异具有统计学意义;观察组治疗后NO、ET-1与对照组相比显著降低,P<0.05,差异具有统计学意义。结论:半夏白术天麻汤中对天麻采用改良后的煎服法,治疗效果提升明显,建议临床应用。

Objective：To treat hypertension with Banxiabaizhutianma and observe the different effect of Gastrodia elata decocting and dosing method on clinical efficacy.Methods：100 patients with primary hypertension were randomly divided into observation group and control group.50 cases in the observation group adopted improved decocting and dosing method,and 50 cases in the control group adopted traditional decoction method.Observe the e treatment efficiency and NO,ET-1 and other indicators after treatment of the two groups.Results：The effective rate of observation group was significantly higher than that of the control group,P〈0.05,and the difference was statistically significant;compared with the control group,the NO,ET-1 of the observation group after treatment decreased significantly,P〈0.05,the difference was statistically significant.Conclusion：The application of improved decoction of Gastrodia elata in Banxiabaizhutianma can obviously improve the treatment effect,and it is suggested for clinical application.