摘要
雷公藤甲素是中药雷公藤的主要活性成分。目前雷公藤甲素已被用作多种疾病的治疗,包括:狼疮,肿瘤,类风湿性关节炎,肾病综合征等。雷公藤甲素的主要药理作用包括:抗炎、抗肿瘤、免疫抑制等,近期研究表明雷公藤甲素对心血管疾病及骨质疏松均有保护作用。该文以近期雷公藤甲素的研究进展为基础,对雷公藤甲素的药理作用进行综述。
Triptolide is an active component in traditional Chinese medicine Tripterygium wilfordii. Currently, triptolide has been used to treat various diseases, including lupus, cancer, rheumatoid arthritis and nephritic syndrome. Its main pharmacology efficacies include anti-inflammation, anti-tumor, and immunity suppression. Recent studies have also demonstrated triptolide＇s protective effect on cardiovascular diseases and osteoporosis. This paper summarizes the pharmacological efficacy of triptolide based on the advance in studies of triptolide.
作者
崔进
陈晓
苏佳灿
CUI Jin CHEN Xiao SU Jia-can(Department of Trauma Orthopedics, Changhai Hospital, Second Military Medical University, Shanghai 200433, Chin)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2017年第14期2655-2658,共4页
China Journal of Chinese Materia Medica
基金
上海市科学技术委员会科研项目(15411950600)
关键词
雷公藤甲素
药理作用
肿瘤
炎症
骨质疏松
triptolide
pharmacological activity
tumor
inflammation
osteoporosis
