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他克莫司在狼疮肾炎中应用的中国专家共识 被引量:13

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摘要 LN是预测SLE患者预后的重要因素之一。目前,用于治疗LN的免疫抑制剂主要包括环磷酰胺、吗替麦考酚酯和硫唑嘌呤等,而越来越多的证据表明,他克莫司(又称FK506)用于LN具有较好的疗效和安全性,为LN的治疗提供了新的选择。他克莫司是从链霉菌属中分离出的大环内酯类药,有很强的免疫抑制作用,能专一地结合及抑制钙调蛋白磷酸酶活性。
出处 《中华风湿病学杂志》 CSCD 北大核心 2017年第7期483-485,共3页 Chinese Journal of Rheumatology
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