三维超声VOCAL分析技术评价胎儿透明隔腔发育的临床意义

Clinical significance of three-dimensional ultrasound VOCAL analysis in the evaluation of fetus cavum septi pellucidi

目的探讨采用三维超声计算机辅助虚拟脏器(VOCAL)分析技术评价胎儿透明隔腔发育的临床意义。方法采用三维超声VOCAL分析技术对160例20~38周胎儿透明隔腔的宽度、前后径以及容积进行检测,对测值(透明隔腔宽度、透明隔腔前后径以及透明隔腔容积)与孕周进行回归分析。结果胎儿透明隔腔宽度与胎儿孕周、头围、小脑横径、双顶径呈正相关(r分别=0.46、0.44、0.48、0.50,P均<0.05);透明隔腔前后径与胎儿孕周、头围、小脑横径以双顶径呈正相关(r分别=0.54、0.53、0.61、0.59,P均<0.05);胎儿透明隔腔容积与胎儿孕周、头围、小脑横径以双顶径呈正相关(r分别=0.45、0.43、0.47、0.48,P均<0.05)。结论胎儿透明隔腔宽度、前后径及容积与胎儿孕周、双顶径、头围及小脑横径存在相关性。三维超声VOCAL分析技术能够立体地显示透明隔腔,更好地评价胎儿透明隔腔发育情况,对产前诊断和处理具有一定的临床价值。

Objective To evaluate the clinical significance of three-dimensional ultrasound virtual computer assisted virtual organ（VOCAL）analysis in the evaluation of cavum septi pellucidi（CSP）. Methods The CSP width,anteroposterior diameter and volume of the 160 cases of 20-38 weeks fetus were detected by using three-dimensional VOCAL technique,and their correlation with gestational age were analyzed by regression analysis.Results The CSP width was positively relate to the fetal gestational age,head circumference（HC）,transverse cerebellar diameter,and biparietal diameter（BPD）（r=0.46,0.44,0.48,0.50,P〈0.05）.The anteroposterior diameter was positively relate to the fetal gestational age,HC,transverse cerebellar diameter,and BPD（r=0.54,0.53,0.61,0.59,P〈0.05）. The anteroposterior volume was positively relate to the gestational age,head circumference（HC）,transverse cerebellar diameter,and BPD（r=0.45,0.43,0.47,0.48,P〈0.05）. Conclusion The CSP width,anteroposterior diameter and volume were correlated with gestational age,BPD,HC,and transverse diameter. VOCAL analysis of three-dimensional ultrasound technology can display pseudocele for better evaluation of fetal pseudocele development. It has certain clinical value on prenatal diagnosis and treatment.