胰岛素治疗PGDM于不同血糖检测标准的妊娠结局分析

Analysis of pregnancy outcomes in PGDM women with insulin therapy to different blood glucose testing standards

目的 分析胰岛素治疗的糖尿病合并妊娠（PGDM）孕妇,了解达到不同血糖控制标准的母婴结局.方法 108例PGDM患者随机分为两组,治疗A组54例控制血糖在妊娠糖尿病（GDM）标准;治疗B组54例控制血糖在PGDM标准.观察两组孕妇妊娠并发症、妊娠结局及新生儿情况.结果 A组孕妇的并发症如妊娠期高血压疾病、羊水过多、阴道炎发生率低于B组,差异有显著性（P〈0.05）;新生儿结局中A组巨大儿、新生儿低血糖发生率低于B组,差异有显著性（P〈0.05）.结论 建议PGDM孕妇在孕期不发生低血糖情况下将血糖控制在空腹及餐后2小时血糖≤5.3、6.7 mmol/L,HbA1c〈5.5%,其孕期并发症将有一定程度减少,而新生儿结局不受影响.

Objective To investigate the relationship of different blood glucose control standard and pregnancy outcomes by analysising（diabetes in pregnancy）PGDM women after insulin treatment.Methods 108 PGDM women who were randomly divided into two groups：A group of 54 cases of treatment to control blood glucose to GDM standard;B group of 54 cases of treatment to control blood glucose to PGDM standard.The pregnancy complications and outcomes of the two groups were observedand the case of newborns.Results The incidence of A group of obstetric complications such as gestational hypertension、polyhydramnios、vaginitis was lower than B group,there was statistically significant（P〈0.05）.The incidence of A group of newborns outcomes such as macrosomia、neonatal hypoglycemia was lower than B group,there was statistically significant（P〈0.05）.Conclusion PGDM pregnant women under no conditions of hypoglycemia should control blood glucose in the following ranges：fasting and 2-hour postprandial blood glucose≤5.3、6.7 mmol/L,HbA1c〈5.5%,it will reduce pregnancy complications to some extent,and neonatal outcomes will not affected.