早期胃癌与进展期胃癌回顾分析的临床价值

Clinical Value of Early Gastric Cancer and Advanced Gastric Cancer by Retrospectiving Analysis

目的回顾分析早期胃癌和进展期胃癌的胃镜下不同和病理特点。方法收集我院2010年1月至2015年6胃镜检查发现并经病理确诊的36例早期胃癌患者和208例进展期胃癌患者的临床资料,进行回顾性分析,比较两组患者的内镜下表现和病理特点。结果早期胃癌病灶多位于胃窦部44.4%(16/36),病理分型以分化型为主88.9%(32/36),进展期胃癌多位于胃底/贲门部46.2%(96/208),病理分型以未分化型为主89.4%(186/208)。二者在病变分布和病理分型构成方面差异有显著性(P<0.05),有统计学意义。结论应用NBI放大成像技术和靛胭脂染色有助于观察早期胃癌的边界和表面形态,通过与进展期胃癌的内镜下和病理不同特点进行比较,有利于及早发现早期胃癌,利于患者的预后。

Objective Retrospectiving analysis the different of electronic gastroscopy characteristics and pathological characteristics about early gastric cancer and advanced gastric cancer. Methods Collecting 36 gastric cancer patients and 208 advanced gastric cancer patients detected at our hospital by electronic gastroscopy and pathological characteristics from Janurary 2010 to June 2015. By retrospectiving analysis, comparing the differents of electronic gastroscopy haracteristics and pathological characteristics. Results The antrum was the most commonly affected in early gastric cancer cases（44.4%,16/36）.Early gastric cancers were mostly pathologicallly differentiated adenocarcinoma（88.9%,32/36）, The fundus or cardia was the most commonly affected in advanced gastric cancer cases（46.2%, 96/208）. Advanced gastric cancer were mostly pathologicallly undifferentiated adenocarcinoma（89.4%,186/208）.There were significant differences in lesion distribution and pathological typing between the two diseases（P〈0.05）. Conclusion Applying NBI enlarge imaging technology and indigocarmine staining were helping to observing border and surpace morphology of early gastric cancer. By comparing electronic gastroscopy characteristics and pathological characteristics about advanced gastric cancer, which facilitate screening and diagnosis of this disease, this was benefit to prognosis of patients.