吲达帕胺联合氨氯地平治疗高血压合并冠心病患者的临床疗效

The Clinical Curative Effect of Indapamide and Amlodipine in the Treatment of Patients With Hypertension and Coronary Heart Disease

目的观察吲达帕胺联合氨氯地平治疗高血压合并冠心病的临床疗效。方法将我院2015年7月—2017年4月收治的128例高血压合并冠心病患者随机分为观察组和对照组,每组64例,对照组应用硝苯地平控释片治疗,观察组联合应用吲达帕胺与氨氯地平治疗,比较两组治疗前后血压及血脂水平,记录治疗期间不良反应发生情况。结果治疗后两组血压和血脂水平均低于治疗前,且观察组上述观察指标降低更加显著(P<0.05)。两组不良反应发生率之间对比,差异无统计学意义(P>0.05)。结论吲达帕胺联合氨氯地平可以改善高血压合并冠心病患者血压和血脂水平,且安全性较高。

Objective To observe the clinical effect of indapamide and amlodipine in the treatment of hypertension and coronary heart disease. Methods 128 patients with hypertension and coronary heart disease in our hospital from July 2015 to April 2017 were randomly divided into the observation group and the control group, 64 cases in each group, control group used nifedipine controlled release tablets treatment, the observation group combined with indapamide and amlodipine treatment, blood pressure and blood lipid levels of the two groups were compared before and after treatment, and the adverse reactions during the treatment were recorded. Results After treatment, the blood pressure and blood lipid levels of the two groups were lower than before treatment, and the observation group was lower significantly（P〈0.05）. There was no significant difference between the two groups in the incidence of adverse reactions（P〉0.05）. ConclusionIndapamide combined with amlodipine can improve blood pressure and blood lipid level in patients with coronary heart disease and hypertension,high security.