不同病原导致和多因素影响的机体应答反应能一样吗？——脓毒症的异质性与多样性

Could the responses for different pathogen with multiple affecting predisposing factors be similar？ --the heterogeneity or diversity of sepsis

脓毒症的异质性与多样性，评价脓毒症的定义和相关专业指南在脓毒症临床诊疗中的作用，脓毒症的核心诊疗依据等逐步受到同行关注。以下就致病原因、个人因素、肠源性因素、基础状态或疾病状态、同期干预等对脓毒症异质性与多样性的影响进行讨论，将各版本的脓毒症国际定义、拯救脓毒症运动的脓毒症与脓毒性休克管理指南和其他相关的专业指南中推荐的一些建议、方法、药物治疗、治疗等作比较，指出进步之处，也注意发现不足之处。

The heterogeneity and diversity of sepsis, evaluation for the role of definitions and related guidelines, and the key evidence for the diagnosis and therapies of sepsis are being paid close attention to. Here are the discussions for the heterogeneity or diversity of sepsis effected from etiology,personality,gut-de- rived problem, predisposing factors or premorbid conditions, co-intervention, with comparing the positive and negative changes on some of the recommendations, suggestions, techniques, medicine, and therapies amongst different editions of International Consensus Definition for Sepsis and Septic Shock, and International Guidelines for Management of Sepsis and Septic Shock in Surviving Sepsis Campaign or other related special procedures.