2016国际脓毒症和脓毒性休克管理指南——需要关注的变化

Surviving Sepsis Guidelines 2016：continuous changes in sepsis managements

国际专家组对“拯救脓毒症运动：2012版脓毒症和脓毒性休克管理指南”进行了更新，结果发表于Critical Care Medicme杂志。新版指南在循证证据的基础上提出了一些新的推荐意见，指南最大的变化是初始复苏策略及抗生素的应用。本文重点就主要的变化以及变化的依据做一解读。

The Surviving Sepsis Guidelines were first published in 2004, with revisions in 2008 and 2012. In January 2017 ,the fourth revision of the Surviving Sepsis Guidelines was presented at the 46th annual SCCM meeting and published online in Critical Care Medicine. The updated guideline was generated by 55 international experts and providing 93 recommendations on early management of sepsis and septic shock. There are numerous major advances in the revision of the guidelines. Among the various topics covered, initial resuscitation and antibiotic therapy are the domains in which the most important changes and advances were made.