摘要
宫颈腺癌综合治疗后(手术和/或放疗后)卵巢功能降低甚至丧失,引起近期绝经症状及某些远期疾病,如高血压、冠心病、糖尿病及骨质疏松等,严重影响患者生活质量。绝经激素治疗能够有效缓解上述症状,显著提高生活质量,但其在宫颈腺癌患者的使用安全性问题上一直饱受争议。近年来随着相关临床试验的进展,该观点正在逐渐发生转变。
After comprehensive treatment (surgery and/or radiotherapy) of cervical adenocarcino- ma,ovarian function decreases or even gets lost,which cause the recent menopausal symptoms and some long-term diseases such as hypertension,coronary heart disease,diabetes and osteo- porosis,which seriously affect the patients' life quality. Menopausal hormone therapy effectively alleviates these symptoms, significantly improve the patient's life quality ,but its security in pa- tients with cervical adenocarcinoma has always been controversial. In recent years,with the progress of related clinical trials, this view is gradually changing.
出处
《肿瘤学杂志》
CAS
2017年第7期627-630,共4页
Journal of Chinese Oncology
关键词
宫颈腺癌
绝经综合征
绝经激素治疗
cervical adenocarcinoma
menopausal syndrome
menopausal hormone therapy