应激性高血糖对ICU危重症患者心功能的影响及强化胰岛素治疗观察

Effect of stress hyperglycemia on cardiac function in critically ill patients with ICU and observation of intensive insulin therapy

目的探究应激性高血糖(SHG)对ICU危重症患者心功能的影响及强化胰岛素治疗的临床疗效。方法选取危重症患者78例,入院后对血糖监测,血糖水平正常为正常血糖组(n=28),血糖水平升高为SHG组(n=50),将血糖水平升高的50例患者随机分为强化治疗组、常规治疗组。比较正常血糖组、SHG组心功能指标情况,以及血糖水平升高的50例患者强化治疗组、常规治疗组治疗前后心功能变化。结果 SHG组心功能指标较正常血糖组差,P<0.05,有区别。强化治疗组、常规治疗组治疗后强化治疗组各项心功能指标明显优于常规治疗组,P<0.05,有区别。结论应激性高血糖(SHG)影响ICU危重症患者的心功能,予以强化胰岛素治疗,可显著改善心功能。

Objective：To investigate the effect of stress hyperglycemia （SHG） on cardiac function in ICU critically ill pa- tients and the clinical efficacy of intensive insulin therapy. Methods ：78 patients with critically ill patients were enrolled in the study. Blood glucose level was normal blood glucose（n =28）, blood glucose level was increased to SHG group （n =50）, 50 patients with elevated blood glucose level Were randomly divided into intensive treatment group, conventional treatment group. Compared with the normal blood glucose group, the cardiac function of the SHG group and the 50 patients with elevated blood glucose level, the treatment group and the conventional treatment group had significant changes in cardiac function before and after treatment. Results ： The cardiac function of SHG group was worse than that of normal blood glucose group （ P 〈 0. 05 ）. In the intensive treatment group and the conventional treatment group, the cardiac function indexes of the intensive treatment group were significantly better than those of the conventional treatment group （P 〈 0. 05 ）. Conclusion ： Stress hyperglycemia （SHG） affects the cardiac function of ICU critically ill patients, and strengthens insulin treatment, which can significantly im- prove cardiac function.