宫颈冷刀锥形切除术与宫颈环形电切术治疗宫颈上皮内瘤变Ⅱ级的效果对比

目的:比较使用宫颈冷刀锥形切除术(CKC)与宫颈环形电切术(LEEP)治疗宫颈上皮内瘤变(CIN)Ⅱ级的效果。方法:选取2015年1月至2016年1月期间成都市新津县武阳社区卫生服务中心收治的66例CINⅡ级患者作为研究对象。随机将这些患者分为CKC组和LEEP组。为CKC组患者使用CKC进行治疗,为LEEP组患者使用LEEP进行治疗。然后比较两组患者治疗的效果、手术指标、术后住院的时间及住院的费用。结果:LEEP组患者的平均术中出血量少于CKC组患者,其手术持续的时间、切口愈合的时间、术后住院的时间均短于CKC组患者,其住院费用少于CKC组患者,差异有统计学意义(P<0.05)。两组患者的治愈率、持续存在率、手术残留率及复发率相比,差异均无统计学意义(P>0.05)。结论:使用LEEP和CKC治疗CINⅡ级均可取得较好的效果。但与使用CKC相比,使用LEEP治疗CINⅡ级手术持续的时间更短,患者的术中出血量更少,其切口愈合的速度更快,住院的时间更短,住院的费用更低。

Objective： To compare the application effect of loop electrosurgical excision procedure （LEEP） and cervical cold knife conization （CKC） for cervical intraepithelial neoplasia Ⅱ （CIN Ⅱ ）. Methods： Randomly select 66 cases of CIN Ⅱ treated in Wuyang community health service centre of Xinjin county from January 2015 to January 2016 for research object. Divide 60 cases into CKC group and LEEP group. CKC group receive CKC surgery, LEEP group receive LEEP surgery, compare curative effect, operation indicator, length of stay and expenditure of 2 groups . Results： Intraoperative blood loss of LEEP group is less than CKC group, operation duration ,healing time of operative incision and length of stay of LEEP group arc shorter than CKC group （P 〈 0.05）. Difference of cure rate, the residual CIN, rate of residue after operation and recurrence rate of two group have no statistical significant （ P 〉 0.05 ） Conclusion： Application effect of CKC and LEEP for CIN Ⅱ are good, but compare with CKC, apply LEEP on CIN Ⅱ patient can shorten operation duration, length of stay and healing time of operative incision are more shorter, decrease intraoperative blood loss during operation and expenditure.