消瘀康胶囊对高血压性脑出血患者血肿吸收期的神经功能影响

The Effect of Xiaoyukang Capsule on the Absorption of Hematoma and Neurological Function in Patients with Hypertensive Intracerebral Hemorrhage

目的:研究消瘀康胶囊对高血压性脑出血患者血肿吸收期的神经功能影响。方法:选择2014年11月1日2015年11月1日我院收治的高血压性脑出血患者110例作为研究对象进行分析。并将其随机分为观察组和对照组各55例。给予对照组患者常规方法进行治疗,观察组则在常规治疗的基础上口服消瘀康胶囊。分别对2组患者在治疗后第7天和14天的脑血肿量及其周围的水肿量、神经功能缺损评分、疗效及治疗后的不良反应情况进行监测和统计。结果:治疗前,2组患者血肿量及其周围水肿量差异不明显(P>0.05)。分别治疗7 d和14 d后,检测到2组患者的血肿量及其周围水肿量均有所降低,且观察组患者的降低程度明显高于对照组,差异有统计学意义(P<0.05)。治疗前,2组患者的神经功能评分差异不明显(P>0.05)。治疗7 d及14 d后,2组患者的神经功能缺损评分均有显著的降低,且观察组患者的减分程度明显高于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者的总有效率为95.55%,对照组患者的总有效率为76.36%,观察组的总有效率高于对照组的总有效率,差异有统计学意义(P<0.05)。结论:加用消瘀康胶囊可以促进血肿周围的水肿吸收,加快患者神经功能的恢复,提高患者的治疗疗效及用药安全性。

Objective：To investigate the the effect of Xiaoyukang capsule on the absorption of hematoma and neurological function in patients with hypertensive intracerebral hemorrhage.Methods：Select 110 patients with hypertensive intracerebral hemorrhage in our hospital enrolled from 1 st November 2014 to 1 st November 2015.Then randomly divided them into observation group and control group,and each of 55 cases.Administered to the control group was conventional methods of treatment,the observation group was Xiaoyukang capsule besides the conventional treatment.Observe edema,cerebral hematoma and the amount of around neurological deficit scores,efficacy and adverse reactions after 7 d and 14 d oftreatment.Results：Before treatment,peripheral edema hematoma volume between groups has no significant difference （P 〉0.05）.After 7 d and 14 d of treatment,the hematoma edema volume in both groups decreased,and the observation group were decreased significantly greater （P 〈 0.05）.Before treatment,neurological functional scores between the two groups were not significantly different （P 〉 0.05） while after treatment of 7 d and 14 d,neurological impairment scores of both groups were significantly reduced,and the observation group was significantly greater than the control group （P 〈 0.05）.The total effective rate of the observation group were 95.55%,compared to 76.36% of the control group,the difference was statistically significant （P 〈 0.05）.Conclusion：Xiaoyukang capsule can promote the absorption of edema around the hematoma,accelerate the recovery of neurological function,improve patient drug efficacy and safety.