颈动脉粥样硬化斑块进展与脑缺血事件相关性的影像学研究进展

Advances in the Imaging Studies on Association between Carotid Atherosclerotic Plaque Progression and Ischemic Cerebrovascular Events

颈动脉粥样硬化斑块进展是导致缺血性脑血管事件的重要病理生理过程。斑块进展可表现为管壁增厚、管腔狭窄或闭塞、脂质核增大、斑块内出血、纤维帽破裂等特征。随着血管影像技术的发展,以评价斑块进展为目的的前瞻性研究越来越广泛。大量研究表明,斑块进展与未来脑血管事件的发生显著相关。本文将对评价斑块的影像学方法的可重复性以及斑块进展与未来脑血管事件相关性影像学研究进展进行综述,旨在更好地理解脑血管病的发病过程,并为疾病的预防提供重要依据。

The progression of carotid atherosclerotic plaques plays an important role in the pathophysiological process of ischemic cerebrovascular events. The progression of atherosclerotic plaque is characterized as wall thickening, luminal stenosis or occlusion, enlargement of lipidrich necrotic core, intraplaque hemorrhage, and fibrous cap disruption, et al. With the development of vascular imaging techniques, prospective studies aimed to assess plaque progression have been extensively performed. A number of studies have demonstrated that atherosclerotic plaque progression is significantly associated with future cerebrovascular events. This review will summarize the reproducibility of various imaging modalities in measuring carotid plaque progression and relationships between plaque progression and ischemic cerebrovascular events This review will be helpful for better understanding the development of cerebrovascular disease and provide vital evidence for disease prevention.