期刊文献+

脑损伤后神经免疫调控的研究进展

原文传递
导出
摘要 创伤性脑创伤(traumatic braini.jury,TBI)是45岁以下人群致死和致残的主要原因。影响TBI患者预后的因素除了原发性脑损伤外,还包括继发性脑病理生理损伤,通常发生于原发性损伤后的几小时至数月,多种神经化学物质和病理生理应答反应在损伤脑组织中产生一种复杂的微环境,进一步损害神经功能。
出处 《中华创伤杂志》 CAS CSCD 北大核心 2017年第8期765-768,共4页 Chinese Journal of Trauma
基金 国家自然科学基金(81271375)
  • 相关文献

参考文献2

二级参考文献13

  • 1Besedovsky HO,del Rey A.Immune-neuro-endocrine inter-actions:facts and hypotheses[J].Endocr Rev,1996,17(1):64-102.
  • 2Quan N,Banks WA.Brain-immune communication pathways[J].Brain Behav Immun,2007,21(6):727-735.
  • 3Capuron L,Miller AH.Immune system to brain signaling:neuropsychopharmacological implications[J].PharmacolTher,2011,130:226-238.
  • 4Gao Y,Ng YK,Lin JY,et al.Expression of immnuoregula-tory cytokines in neurons of the lateral hypothalamic area and amygdaloid nuclear complex of rats immunized against human IgG[J].Brain Res,2000,859(2):364-368.
  • 5Berczi I,Arnason BG.The hypothalamus is the central organ of immunoregulation[J].Neuroimmune Biology,2010,9:3-9.
  • 6Konsman JP,Tridon V,Dantzer R.Diffusion and action of intracerebroventricularly injected interleukin-1in the CNS[J].Neuroscience,2000,101(4):957-967.
  • 7Sugama S,Takenouchi T,Fujita M,et al.Cold stress induced morphological microglial activation and increased IL-1βex-pression in astroglial cells in rat brain[J].J Neuroimmunol,2011,233:29-36.
  • 8John B,Harris TH,Tait ED,et al.Dynamic imaging of CD8+T cells and dendritic cells during infection with Toxo-plasma gondii[J].PLoS Pathog,2009,5(7):1-15.
  • 9Wortis HH,Nehlsen S,Owen JJ.Abnormal development of the thymus in“nude”mice[J].J Exp Med,1971,134:681-692.
  • 10Asano M,Toda M,Sakaguchi N,et al.Autoimmune disease as a consequence of developmental abnormality of a T Cell Subpopulation[J].J Exp Med,1996,184(2):387-396.

共引文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部