罐药并用对围绝经期综合征患者生活质量和雌激素水平影响

Effect of Cupping plus Medication on Quality of Life and Estrogen Level in Perimenopausal Syndrome Patients

目的观察罐药并用对围绝经期综合征患者生活质量和雌激素水平的影响。方法选择符合标准的围绝经期综合征患者40例,将患者按就诊的先后顺序随机分为罐药组和中药组,每组20例。中药组给予二仙汤进行治疗;罐药组在二仙汤治疗的基础上进行背部走罐,每星期治疗1次。观察两组治疗前后MENQOL各维度评分及血清中雌二醇(E_2)、促卵泡激素(FSH)和促黄体生成素(LH)的水平变化,并对统计结果进行分析。结果经2个疗程治疗后两组MENQOL的血管舒缩症状、心理状态、生理状态、性生活评分均较治疗前有显著改善(P<0.05,P<0.01),两组总分比较差异有统计学意义(P<0.01),治疗后组间比较显示,罐药组明显优于中药组(P<0.05)。治疗2个疗程后两组血清中E_2水平均较治疗前明显升高(P<0.01),且罐药组比中药组升高明显(P<0.05),FSH水平和LH水平均较治疗前有所降低,但无统计学意义(P>0.05)。结论背部走罐配合二仙汤能有效改善围绝经期综合征患者的生活质量,明显提高血清中E2水平,优于单纯使用二仙汤。

Objective To observe the effect of cupping plus medication on the quality of life and estrogen level in perimenopausal syndrome patients. Method A total of 40 eligible perimenopausal syndrome patients were randomized into a cupping-medication group and a Chinese medication group, 20 cases in each group. The Chinese medication group was intervened by Er Xian decoction, the cupping-medication group was intervened by moving cupping on the back in addition to the treatment given to the Chinese medication group, once a week. Each item of the Menopause-specific Quality of Life（MENQOL）, the levels of estradiol（E_2）, follicle-stimulating hormone（FSH） and luteotropic hormone（LH） in serum were observed before and after the treatment, and the results were analyzed. Result After two treatment courses, the vasomotor symptoms, mental state, physiological state, and sexual life scores in the two groups were significantly improved compared to the scores before the treatment（P〈0.05,P〈0.01）, and there was a significant difference between the two groups in comparing the MENQOL total score（P〈0.01）. The between-group comparison after the treatment showed that the cupping-medication group was significantly superior to the Chinese medication group（P〈0.05）. After two treatment courses, the serum E_2 levels in the two groups were significantly higher than those before the treatment（P〈0.01）, and the increase in the cupping-medication group was more significant than that in the Chinese medication group（P〈0.05）. After the treatment, the serum FSH and LH levels in the two groups were lower compared to those before the treatment, but without statistical significance（P〈0.05）. Conclusion Moving cupping on the back plus Er Xian decoction can effectively improve the quality of life of perimenopausal syndrome patients and significantly increase the serum E_2 level, superior to using Er Xian decoction alone.