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氨氯地平联合缬沙坦对老年高血压患者血压及血管内皮功能的影响 被引量:2

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摘要 目的研究老年高血压采用氨氯地平联合缬沙坦治疗对患者血压及血管内皮功能的影响。方法选取2015年3月至2016年7月汝阳县人民医院收治的82例老年高血压患者,根据随机数表法分为对照组与观察组,各41例。对照组予以缬沙坦治疗,观察组予以氨氯地平+缬沙坦治疗。对比两组血压[24 h平均舒张压(24 h DBP)、24 h平均收缩压(24 h SBP)]及血管内皮功能[大动脉弹性指数(C1)、小动脉弹性指数(C2)、脉搏波传导速度(PWV)]改善状况。结果治疗后观察组24 h DBP、SBP均低于对照组,差异有统计学意义(P<0.05);观察组C1、C2均高于对照组,PWV低于对照组,差异有统计学意义(P<0.05)。结论老年高血压采用氨氯地平与缬沙坦联合治疗可有效控制血压,并能改善患者血管内皮功能。
作者 熊群武
出处 《河南医学研究》 CAS 2017年第15期2821-2822,共2页 Henan Medical Research
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