2013—2016年某综合性三级甲等医院质子泵抑制剂应用分析

Analysis on Application of Proton Pump Inhibitors in A Comprehensive 3-A Grade Hospital During 2013-2016

目的:了解2013—2016年某综合性三级甲等医院(以下简称"该院")质子泵抑制剂应用情况,为合理用药提供参考。方法:对2013—2016年该院门诊及住院患者应用质子泵抑制剂的品种、使用量、销售金额、用药频度、限定日费用、药品销售金额排序(B)/DDDs排序(A)等进行回顾性统计分析。结果:2013—2016年,该院质子泵抑制剂的销售金额逐年增长;奥美拉唑肠溶片(10 mg)的用药频度排序均居首位,且其B/A远>1,说明其价格低廉,应用较多;注射用兰索拉唑的销售金额排序均居首位,其B/A远<1,说明其价格较高。结论:该院质子泵抑制剂的使用较合理,但也存在部分不合理用药现象。临床医师应根据临床需要及成本-效果分析,为患者选择价格适宜的药品,以减少患者的经济负担。

OBJECTIVE： To investigate the application of proton pump inhibitors（PPI）in a comprehensive 3-A grade hospital（ hereinafter referred to as ＂this hospital＂）during 2013-2016, and provide references for rational drug application. METHODS： To carry out a retrospective statistical analysis of varieties, usage amount, consumption sum, DDDs, DDC and sequence of consumption sum（ B）/sequence of DDDs（A） of PPI in outpatient of this hospital from 2013 to 2016. RESULTS： From 2013 to 2016, the consumption sum of PPI increased year by year; the DDDs of Omeprazole enteric-coated tablets（ 10 mg） ranked the 1 st, and its B/A was far more than 1, which indicated its low price and wide application; the consumption sum of Lansoprazole injection ranked the 1st, and its B/A was far less than 1, which indicated its high price. CONCLUSIONS： The application of PPI in this hospital is pretty rational, clinicians should choose drugs in reasonable price according to the clinical needs and cost-curative effect, so as to reduce economic burden for patients.